#fda-app{--fda-site-height: 82px;padding-top:var(--fda-site-height);position:relative;isolation:isolate;min-height:80vh;letter-spacing:normal}#fda-app p,#fda-app h1,#fda-app h2,#fda-app h3,#fda-app h4{color:inherit}#fda-app h1,#fda-app h2{max-width:none}body:has(#fda-app) [data-site-header]{background:var(--void)}#fda-app main>:where(section,article):not([data-no-section-rule]){border-top:0!important}#fda-app.fda-module [data-module-header]{top:var(--fda-site-height);z-index:35}#fda-app.fda-explorer .brand .name{display:block}#fda-app.fda-explorer .rail,#fda-app.fda-explorer .panel{top:calc(var(--fda-nav-height, 230px) + 8px);max-height:calc(100dvh - var(--fda-nav-height, 230px) - 16px)}#fda-app.fda-explorer .drawer{z-index:30}#fda-app.fda-explorer .tip{z-index:36}#fda-app .source-card{top:calc(var(--fda-nav-height, 150px) + 16px)}#fda-app .fda-nav-frame,#fda-app.fda-explorer header.top #tabs{width:min(calc(100% - var(--gutter) * 2),var(--wide));max-width:none;margin-inline:auto;padding-inline:0}#fda-app .fda-nav-frame{display:flex;align-items:center;justify-content:flex-start;gap:0 25px;height:auto;min-height:68px;padding-block:0}#fda-app .fda-nav-frame .app-name,#fda-app .fda-nav-frame .brand .name{font-family:var(--font-body);font-size:.875rem;font-weight:700;line-height:1.4;color:var(--text);padding:0;white-space:nowrap}#fda-app.fda-module .fda-primary-nav{display:flex;flex:0 0 auto;align-self:center;align-items:center;gap:22px;height:44px;min-height:44px;max-width:none;margin:0;padding:0;border:0}#fda-app.fda-module .fda-primary-nav a{position:relative;display:flex;align-items:center;min-height:44px;padding:0;border:0;font-size:.875rem;line-height:20px;white-space:nowrap}#fda-app.fda-module .fda-primary-nav a[aria-current=page]:after{content:"";position:absolute;inset:auto 0 5px;height:2px;background:var(--teal)}#fda-app.fda-explorer .top-right{margin-left:auto}@media(max-width:1200px){#fda-app.fda-explorer .top-right .tag{display:none}}@media(max-width:980px){#fda-app .app-nav-inner.fda-nav-frame{flex-wrap:wrap;padding-bottom:12px}#fda-app .app-nav-inner .app-name{padding-block:12px}}@media(max-width:740px){#fda-app .fda-nav-frame{flex-wrap:wrap;row-gap:4px;padding-block:8px}#fda-app .app-nav-inner .app-name{flex-basis:100%;padding-block:4px}#fda-app.fda-module .fda-primary-nav{flex-basis:100%;gap:20px}#fda-app.fda-explorer .fda-primary-nav{order:3}#fda-app.fda-explorer .theme-btn .lbl{position:absolute;width:1px;height:1px;overflow:hidden;clip-path:inset(50%);white-space:nowrap}}#fda-app .control-icon{display:block;width:18px;height:18px;flex:0 0 18px}#fda-app .filter-chip{line-height:1.35;min-height:36px}#fda-app .filter-chip .control-icon{width:14px;height:14px;flex-basis:14px}#fda-app .picker .eyebrow{font-size:.8125rem;letter-spacing:.08em}#fda-app .summary-band .actions{gap:12px}#fda-app .summary-band .button{min-height:44px;padding:10px 15px;gap:10px;font-size:.875rem}#fda-app .text-button:has(.control-icon){display:inline-flex;align-items:center;gap:8px}#fda-app .letter-open{margin-top:12px;min-height:40px;padding:8px 13px;gap:10px;font-size:.8125rem;color:var(--teal)}#fda-app .table-wrap tbody tr:focus-within{background:color-mix(in srgb,var(--signal) 4%,var(--panel))}#fda-app .letter-card-action{display:inline-flex;align-items:center;gap:10px;margin-top:14px;color:var(--teal);font-size:.875rem;font-weight:650}#fda-app .commercial .text-button{text-decoration:none;border-bottom:1px dashed color-mix(in srgb,var(--off-white) 52%,transparent);padding-bottom:3px}#fda-app .commercial .text-button:hover{text-decoration:none;border-bottom-style:solid}#fda-app .method-head{max-width:850px}#fda-app .alert-cadences{border:0;margin:24px 0 18px;padding:0;min-width:0}#fda-app .alert-cadences legend{font-family:Space Grotesk,sans-serif;font-size:1.1rem;font-weight:650;margin-bottom:14px;padding:0}#fda-app .alert-cadence{display:flex;align-items:flex-start;gap:12px;margin-top:10px;padding:15px;border:1px solid var(--line);border-radius:10px;background:var(--panel);cursor:pointer}#fda-app .alert-cadence:has(input:checked){border-color:var(--teal);background:color-mix(in srgb,var(--signal) 6%,var(--panel))}#fda-app .alert-cadence:focus-within{outline:2px solid var(--blue);outline-offset:3px}#fda-app .alert-cadence input{width:18px;height:18px;flex:0 0 18px;margin:3px 0 0;accent-color:var(--teal)}#fda-app .alert-cadence strong,#fda-app .alert-cadence small{display:block}#fda-app .alert-cadence small{margin-top:4px;color:var(--muted);line-height:1.5}#fda-app .alert-save-note{margin-top:18px}#fda-app #alertsDialog .dialog-head{position:sticky;top:0;z-index:1;background:var(--panel)}#fda-app #alertsDialog .hs-form-frame{min-width:0}#fda-app #alertsDialog .hs-form-frame iframe{display:block;width:100%;border:0}#fda-app.fda-explorer .hero{display:block;padding:20px 0 28px}#fda-app.fda-explorer .search-row{display:block;margin-top:0}#fda-app.fda-explorer .search-row .search{width:100%;max-width:none;min-width:0;margin:0;height:50px}#fda-app.fda-explorer .search-row .search input{font-size:1rem}#fda-app.fda-explorer .top-in.fda-nav-frame{flex-wrap:wrap;padding-bottom:10px}#fda-app.fda-explorer .top-in .brand,#fda-app.fda-explorer .top-in .top-right{min-height:58px}#fda-app.fda-explorer .explorer-search-tools{display:flex;align-items:center;gap:12px;flex-basis:100%;min-width:0}#fda-app.fda-explorer .explorer-search-tools .search-row{flex:1;min-width:0}#fda-app.fda-explorer .explorer-search-tools .search{height:42px}#fda-app.fda-explorer .explorer-search-tools .search input{font-size:.875rem}#fda-app.fda-explorer .explorer-search-tools .suggest{left:0;width:100%;max-height:min(340px,45dvh)}#fda-app.fda-explorer .explorer-search-tools>button{flex-shrink:0;min-height:42px}#fda-app.fda-module [data-fda-share],#fda-app.fda-explorer :is(.fda-share-cta,.fda-alerts-cta){background:var(--signal);border-color:var(--signal);color:var(--on-fill, var(--void));font-weight:700;justify-content:center;border-radius:999px}#fda-app.fda-module [data-fda-share]:hover,#fda-app.fda-explorer :is(.fda-share-cta,.fda-alerts-cta):hover{background:color-mix(in srgb,var(--signal) 88%,var(--off-white));border-color:var(--signal);color:var(--on-fill, var(--void))}#fda-app.fda-module [data-fda-share]:focus-visible,#fda-app.fda-explorer :is(.fda-share-cta,.fda-alerts-cta):focus-visible{outline:3px solid var(--depth);outline-offset:3px}#fda-app.fda-module [data-fda-share]{display:inline-flex;align-items:center;gap:10px;min-height:44px;padding:10px 15px;text-decoration:none;line-height:1.3}#fda-app.fda-explorer .subscribe-card{margin:0;padding:24px;border:1px solid var(--border);border-radius:16px;background:var(--surface);min-width:0;align-self:start;grid-column:auto}#fda-app.fda-explorer .subscribe-card h3{margin-bottom:10px;font-size:18px;color:var(--text)}#fda-app.fda-explorer .subscribe-card p{font-size:.875rem;line-height:1.6;color:var(--text-muted)}#fda-app.fda-explorer .subscribe-card .actions{margin-block:16px 12px}#fda-app.fda-explorer .fda-alerts-cta{min-height:48px;padding:12px 19px;gap:18px;font-size:.875rem}#fda-app.fda-explorer #alertsDialog{--panel: var(--surface);--line: var(--border);--muted: var(--text-muted);width:min(590px,calc(100vw - 32px));max-height:calc(100dvh - 32px);margin:auto;padding:0;border:1px solid var(--line);border-radius:16px;background:var(--panel);color:var(--text);box-shadow:var(--shadow);overflow:auto}#fda-app.fda-explorer #alertsDialog::backdrop{background:var(--void);opacity:.6}#fda-app.fda-explorer #alertsDialog .dialog-head{display:flex;align-items:center;justify-content:space-between;gap:16px;padding:24px;border-bottom:1px solid var(--line)}#fda-app.fda-explorer #alertsDialog h2{font-size:1.5rem}#fda-app.fda-explorer #alertsDialog [data-close-alerts]{min-width:44px;min-height:44px;font-size:1.5rem}#fda-app.fda-explorer #alertsDialog .dialog-body{padding:24px}#fda-app.fda-explorer #alertsDialog :is(p,.hs-form-frame){margin-bottom:16px}#fda-app.fda-explorer #alertsDialog :is(button,a):focus-visible{outline:3px solid var(--depth);outline-offset:3px}#fda-app.fda-explorer .top-right .tag{display:none}#fda-app.fda-explorer .hero{padding:0}#fda-app.fda-explorer header.top #tabs{flex-wrap:nowrap;overflow-x:auto;scrollbar-width:thin}#fda-app.fda-explorer .fda-nav-frame .brand .name{overflow:visible;text-overflow:clip}#fda-app.fda-module dialog.fda-share-dialog{width:min(460px,calc(100vw - 32px));max-width:none;max-height:calc(100dvh - 32px);margin:auto;padding:24px;border:1px solid var(--line, var(--border));border-radius:16px;color:var(--text);background:var(--panel, var(--navy));box-shadow:var(--shadow);overflow:auto;font-family:var(--font-body)}#fda-app.fda-module dialog.fda-share-dialog::backdrop{background:var(--void);opacity:.6}#fda-app.fda-explorer dialog.fda-share-dialog{--line: var(--border);--muted: var(--text-muted)}#fda-app .fda-share-heading{display:flex;align-items:center;justify-content:space-between;gap:12px;margin-bottom:12px}#fda-app .fda-share-heading h2{font-size:1.45rem;margin:0;letter-spacing:-.025em}#fda-app .fda-share-dialog button,#fda-app .fda-share-dialog a{display:inline-flex;align-items:center;justify-content:center;gap:8px;min-height:44px;padding:8px 14px;border:1px solid var(--line, var(--border));border-radius:8px;color:var(--text);background:transparent;text-decoration:none;font:inherit;cursor:pointer}#fda-app .fda-share-heading button{font-size:1.5rem;min-width:44px;padding:4px}#fda-app .fda-share-dialog label{display:block;font-size:.8rem;font-weight:650;margin:18px 0 6px}#fda-app .fda-share-dialog input{box-sizing:border-box;width:100%;min-width:0;border:1px solid var(--line, var(--border));border-radius:8px;padding:12px;background:var(--bg, var(--void));color:var(--text);font:inherit;font-size:.8rem}#fda-app .fda-share-actions{display:flex;gap:8px;flex-wrap:wrap;margin-top:14px}#fda-app .fda-share-actions>*{flex:1}#fda-app #fdaShareCopy{background:var(--signal);border-color:var(--signal);color:var(--on-fill, var(--void));font-weight:650}#fda-app .fda-share-dialog :is(button,a,input):focus-visible{outline:2px solid var(--depth);outline-offset:3px}#fda-app #fdaShareDescription{font-size:.95rem;line-height:1.5}#fda-app #fdaShareStatus{min-height:1.5em;margin:12px 0 6px;font-size:.85rem}#fda-app .fda-share-note{font-size:.75rem;line-height:1.5;color:var(--muted, var(--text-muted));margin:0}@media(min-width:1400px){#fda-app.fda-explorer .top-in.fda-nav-frame{padding-bottom:0;flex-wrap:nowrap;gap:18px}#fda-app.fda-explorer .explorer-search-tools{flex:1;order:2}#fda-app.fda-explorer .top-right{order:3}}@media(max-width:740px){#fda-app.fda-explorer .explorer-search-tools{order:4}#fda-app.fda-explorer .top-in .brand,#fda-app.fda-explorer .top-in .top-right{min-height:36px}#fda-app.fda-explorer .top-in.fda-nav-frame{row-gap:8px}#fda-app.fda-explorer .explorer-search-tools>button{padding-inline:10px;font-size:.8rem}}@media(max-width:1100px){#fda-app.fda-explorer .rail,#fda-app.fda-explorer .panel{max-height:none}}@media(max-width:700px){#fda-app.fda-explorer .brand .name{white-space:normal;font-size:13px}}#fda-app .fda-server-summary{padding:24px;margin-bottom:24px}#fda-app .fda-server-summary h2{font-size:1.5rem}#fda-app .fda-server-summary h3{margin-top:24px}#fda-app .fda-server-summary table{width:100%;border-collapse:collapse;font-size:.875rem}#fda-app [data-server-rendered] caption,#fda-app .fda-server-summary caption{text-align:left;font-weight:650;padding-block:16px 8px}#fda-app .fda-server-summary :is(th,td){padding:8px;text-align:left;border-bottom:1px solid var(--border)}#fda-app .fda-server-summary .latest-card{display:block;padding-block:12px;color:var(--text)}#fda-app .fda-server-summary .latest-card>*{display:block}#fda-app .fda-server-summary .latest-card small{color:var(--text-muted)}#fda-app [data-server-rendered] .table-wrap{overflow-x:auto}#fda-app [data-server-rendered] .latest-card>*{display:block}#fda-app [data-server-rendered] .latest h2{font-size:1.25rem}#fda-app [data-server-rendered] caption{padding-inline:18px}@media print{[data-site-header],.site-footer{display:none!important}#fda-app{padding-top:0}}