#fda-app{--fda-site-height: 82px;padding-top:var(--fda-site-height);position:relative;isolation:isolate;min-height:80vh;letter-spacing:normal}#fda-app p,#fda-app h1,#fda-app h2,#fda-app h3,#fda-app h4{color:inherit}#fda-app h1,#fda-app h2{max-width:none}body:has(#fda-app) [data-site-header]{background:var(--void)}#fda-app main>:where(section,article):not([data-no-section-rule]){border-top:0!important}#fda-app.fda-module [data-module-header]{position:relative;top:auto;z-index:35}#fda-app.fda-explorer .brand .name{display:block}#fda-app.fda-explorer .rail,#fda-app.fda-explorer .panel{top:calc(var(--fda-nav-height, 230px) + 8px);max-height:calc(100dvh - var(--fda-nav-height, 230px) - 16px)}#fda-app.fda-explorer .drawer{z-index:30}#fda-app.fda-explorer .tip{z-index:36}#fda-app .source-card{top:calc(var(--fda-nav-height, 150px) + 16px)}#fda-app .fda-nav-frame,#fda-app.fda-explorer header.top #tabs{width:min(calc(100% - var(--gutter) * 2),var(--wide));max-width:none;margin-inline:auto;padding-inline:0}#fda-app .fda-nav-frame{display:flex;align-items:center;justify-content:flex-start;gap:0 25px;height:auto;min-height:68px;padding-block:0}#fda-app .fda-nav-frame .app-name,#fda-app .fda-nav-frame .brand .name{font-family:var(--font-body);font-size:.875rem;font-weight:700;line-height:1.4;color:var(--text);padding:0;white-space:nowrap}#fda-app.fda-module .fda-primary-nav{display:flex;flex:0 0 auto;align-self:center;align-items:center;gap:22px;height:44px;min-height:44px;max-width:none;margin:0;padding:0;border:0}#fda-app.fda-module .fda-primary-nav a{position:relative;display:flex;align-items:center;min-height:44px;padding:0;border:0;font-size:.875rem;line-height:20px;white-space:nowrap}#fda-app.fda-module .fda-primary-nav a[aria-current=page]:after{content:"";position:absolute;inset:auto 0 5px;height:2px;background:var(--teal)}#fda-app.fda-explorer .top-right{margin-left:auto}@media(max-width:1200px){#fda-app.fda-explorer .top-right .tag{display:none}}@media(max-width:980px){#fda-app .app-nav-inner.fda-nav-frame{flex-wrap:wrap;padding-bottom:12px}#fda-app .app-nav-inner .app-name{padding-block:12px}}@media(max-width:740px){#fda-app .table-wrap.compact :is(th,td):nth-child(2){display:none}#fda-app .table-wrap.compact :is(th,td):nth-child(3){display:table-cell}#fda-app .fda-nav-frame{flex-wrap:wrap;row-gap:4px;padding-block:8px}#fda-app .app-nav-inner .app-name{flex-basis:100%;padding-block:4px}#fda-app.fda-module .fda-primary-nav{flex-basis:100%;gap:20px}#fda-app.fda-explorer .fda-primary-nav{order:3}#fda-app.fda-explorer .theme-btn .lbl{position:absolute;width:1px;height:1px;overflow:hidden;clip-path:inset(50%);white-space:nowrap}}#fda-app .control-icon{display:block;width:18px;height:18px;flex:0 0 18px}#fda-app .filter-chip{line-height:1.35;min-height:36px}#fda-app .filter-chip .control-icon{width:14px;height:14px;flex-basis:14px}#fda-app .text-button:has(.control-icon){display:inline-flex;align-items:center;gap:8px}#fda-app .table-wrap tbody tr:focus-within{background:color-mix(in srgb,var(--signal) 4%,var(--panel))}#fda-app :is(a.latest-card,a.letter-card,a.deeper-link){text-decoration:none}#fda-app a.latest-card{padding-inline:12px;border-radius:8px}#fda-app :is(a.latest-card,a.letter-card,a.deeper-link):is(:hover,:focus-visible){text-decoration:none;border-color:var(--teal);background:color-mix(in srgb,var(--signal) 7%,var(--panel, var(--surface)))}#fda-app .bar-row{padding:4px 6px;border-radius:6px}#fda-app .bar-row:is(:hover,:focus-visible){background:color-mix(in srgb,var(--signal) 7%,var(--panel, var(--surface)))}#fda-app .bar-row:is(:hover,:focus-visible) .bar-label{text-decoration:none;color:var(--teal)}#fda-app :is(a.pill,a.tag),#fda-app .ai-tags button.ai-tag{text-decoration:underline;text-underline-offset:3px;text-decoration-thickness:1px}#fda-app .fda-primary-nav a:hover,#fda-app a.button:hover{text-decoration:none}#fda-app.fda-explorer .p-item{grid-template-columns:minmax(0,1fr);grid-template-areas:"co" "d" "meta";row-gap:4px}#fda-app.fda-explorer .p-item .co{white-space:normal;overflow-wrap:anywhere}#fda-app.fda-explorer .p-item .d{white-space:normal;line-height:1.5}#fda-app.fda-explorer .p-list-head{flex-wrap:wrap}#fda-app.fda-explorer .p-tools{min-width:0;max-width:100%}#fda-app.fda-explorer .p-tools select{max-width:100%}#fda-app.fda-explorer .cfr-letters button{grid-template-columns:minmax(0,1fr);gap:4px}#fda-app.fda-explorer .cfr-letters button>span:not(.d):not(.f){grid-row:1;overflow-wrap:anywhere}#fda-app.fda-explorer .cfr-letters button .d{grid-row:2;line-height:1.5}#fda-app.fda-explorer .cfr-letters button .f{grid-row:3;white-space:normal}#fda-app .commercial .text-button{text-decoration:none;border-bottom:1px dashed color-mix(in srgb,var(--off-white) 52%,transparent);padding-bottom:3px}#fda-app .commercial .text-button:hover{text-decoration:none;border-bottom-style:solid}#fda-app .method-head{max-width:850px}#fda-app .alert-cadence:has(input:checked){border-color:var(--teal);background:color-mix(in srgb,var(--signal) 6%,var(--panel))}#fda-app #alertsDialog .dialog-head{position:sticky;top:0;z-index:1;background:var(--panel)}#fda-app #alertsDialog .hs-form-frame{min-width:0}#fda-app #alertsDialog .hs-form-frame iframe{display:block;width:100%;border:0}#fda-app.fda-explorer .hero{display:block;padding:20px 0 28px}#fda-app.fda-explorer .search-row{display:block;margin-top:0}#fda-app.fda-explorer .search-row .search{width:100%;max-width:none;min-width:0;margin:0;height:50px}#fda-app.fda-explorer .search-row .search input{font-size:1rem}#fda-app.fda-explorer .top-in.fda-nav-frame{flex-wrap:wrap;padding-bottom:10px}#fda-app.fda-explorer .top-in .brand,#fda-app.fda-explorer .top-in .top-right{min-height:58px}#fda-app.fda-explorer .explorer-search-tools{display:flex;align-items:center;gap:12px;flex-basis:100%;min-width:0}#fda-app.fda-explorer .explorer-search-tools .search-row{flex:1;min-width:0}#fda-app.fda-explorer .explorer-search-tools .search{height:42px}#fda-app.fda-explorer .explorer-search-tools .search input{font-size:.875rem}#fda-app.fda-explorer .explorer-search-tools .suggest{left:0;width:100%;max-height:min(340px,45dvh)}#fda-app.fda-explorer .explorer-search-tools>button{flex-shrink:0;min-height:42px}#fda-app.fda-module [data-fda-share],#fda-app.fda-explorer :is(.fda-share-cta,.fda-alerts-cta){background:var(--signal);border-color:var(--signal);color:var(--on-fill, var(--void));font-weight:700;justify-content:center;border-radius:999px}#fda-app.fda-module [data-fda-share]:hover,#fda-app.fda-explorer :is(.fda-share-cta,.fda-alerts-cta):hover{background:color-mix(in srgb,var(--signal) 88%,var(--off-white));border-color:var(--signal);color:var(--on-fill, var(--void))}#fda-app.fda-module [data-fda-share]:focus-visible,#fda-app.fda-explorer :is(.fda-share-cta,.fda-alerts-cta):focus-visible{outline:3px solid var(--depth);outline-offset:3px}#fda-app.fda-module [data-fda-share]{display:inline-flex;align-items:center;gap:10px;min-height:44px;padding:10px 15px;text-decoration:none;line-height:1.3}#fda-app.fda-explorer .subscribe-card{margin:0;padding:24px;border:1px solid var(--border);border-radius:16px;background:var(--surface);min-width:0;align-self:start;grid-column:auto}#fda-app.fda-explorer .subscribe-card h3{margin-bottom:10px;font-size:18px;color:var(--text)}#fda-app.fda-explorer .subscribe-card p{font-size:.875rem;line-height:1.6;color:var(--text-muted)}#fda-app.fda-explorer .subscribe-card .actions{margin-block:16px 12px}#fda-app.fda-explorer .fda-alerts-cta{min-height:48px;padding:12px 19px;gap:18px;font-size:.875rem}#fda-app.fda-explorer #alertsDialog{--panel: var(--surface);--line: var(--border);--muted: var(--text-muted);width:min(590px,calc(100vw - 32px));max-height:calc(100dvh - 32px);margin:auto;padding:0;border:1px solid var(--line);border-radius:16px;background:var(--panel);color:var(--text);box-shadow:var(--shadow);overflow:auto}#fda-app.fda-explorer #alertsDialog::backdrop{background:var(--backdrop)}#fda-app.fda-explorer #alertsDialog .dialog-head{display:flex;align-items:center;justify-content:space-between;gap:16px;padding:24px;border-bottom:1px solid var(--line)}#fda-app.fda-explorer #alertsDialog h2{font-size:1.5rem}#fda-app.fda-explorer #alertsDialog [data-close-alerts]{min-width:44px;min-height:44px;font-size:1.5rem}#fda-app.fda-explorer #alertsDialog .dialog-body{padding:24px}#fda-app.fda-explorer #alertsDialog :is(p,.hs-form-frame){margin-bottom:16px}#fda-app.fda-explorer #alertsDialog :is(button,a):focus-visible{outline:3px solid var(--depth);outline-offset:3px}#fda-app.fda-explorer .top-right .tag{display:none}#fda-app.fda-explorer .hero{padding:0}#fda-app.fda-explorer header.top #tabs{flex-wrap:nowrap;overflow-x:auto;scrollbar-width:thin}#fda-app.fda-explorer .fda-nav-frame .brand .name{overflow:visible;text-overflow:clip}#fda-app.fda-module dialog.fda-share-dialog{width:min(460px,calc(100vw - 32px));max-width:none;max-height:calc(100dvh - 32px);margin:auto;padding:24px;border:1px solid var(--line, var(--border));border-radius:16px;color:var(--text);background:var(--panel, var(--navy));box-shadow:var(--shadow);overflow:auto;font-family:var(--font-body)}#fda-app.fda-module dialog.fda-share-dialog::backdrop{background:var(--backdrop)}#fda-app.fda-explorer dialog.fda-share-dialog{--line: var(--border);--muted: var(--text-muted)}#fda-app .fda-share-heading{display:flex;align-items:center;justify-content:space-between;gap:12px;margin-bottom:12px}#fda-app .fda-share-heading h2{font-size:1.45rem;margin:0;letter-spacing:-.025em}#fda-app .fda-share-dialog button,#fda-app .fda-share-dialog a{display:inline-flex;align-items:center;justify-content:center;gap:8px;min-height:44px;padding:8px 14px;border:1px solid var(--line, var(--border));border-radius:8px;color:var(--text);background:transparent;text-decoration:none;font:inherit;cursor:pointer}#fda-app .fda-share-heading button{font-size:1.5rem;min-width:44px;padding:4px}#fda-app .fda-share-dialog label{display:block;font-size:.8rem;font-weight:650;margin:18px 0 6px}#fda-app .fda-share-dialog input{box-sizing:border-box;width:100%;min-width:0;border:1px solid var(--line, var(--border));border-radius:8px;padding:12px;background:var(--bg, var(--void));color:var(--text);font:inherit;font-size:.8rem}#fda-app .fda-share-actions{display:flex;gap:8px;flex-wrap:wrap;margin-top:14px}#fda-app .fda-share-actions>*{flex:1}#fda-app #fdaShareCopy{background:var(--signal);border-color:var(--signal);color:var(--on-fill, var(--void));font-weight:650}#fda-app .fda-share-dialog :is(button,a,input):focus-visible{outline:2px solid var(--depth);outline-offset:3px}#fda-app #fdaShareDescription{font-size:.95rem;line-height:1.5}#fda-app #fdaShareStatus{min-height:1.5em;margin:12px 0 6px;font-size:.85rem}#fda-app .fda-share-note{font-size:.75rem;line-height:1.5;color:var(--text-muted, var(--muted));margin:0}@media(min-width:1400px){#fda-app.fda-explorer .top-in.fda-nav-frame{padding-bottom:0;flex-wrap:nowrap;gap:18px}#fda-app.fda-explorer .explorer-search-tools{flex:1;order:2}#fda-app.fda-explorer .top-right{order:3}}@media(max-width:740px){#fda-app.fda-explorer .explorer-search-tools{order:4}#fda-app.fda-explorer .top-in .brand,#fda-app.fda-explorer .top-in .top-right{min-height:36px}#fda-app.fda-explorer .top-in.fda-nav-frame{row-gap:8px}#fda-app.fda-explorer .explorer-search-tools>button{padding-inline:10px;font-size:.8rem}}@media(max-width:1100px){#fda-app.fda-explorer .rail,#fda-app.fda-explorer .panel{max-height:none}}@media(max-width:700px){#fda-app.fda-explorer .brand .name{white-space:normal;font-size:13px}}#fda-app .fda-server-summary{padding:24px;margin-bottom:24px}#fda-app .fda-server-summary h2{font-size:1.5rem}#fda-app .fda-server-summary h3{margin-top:24px}#fda-app .fda-server-summary table{width:100%;border-collapse:collapse;font-size:.875rem}#fda-app [data-server-rendered] caption,#fda-app .fda-server-summary caption{text-align:left;font-weight:650;padding-block:16px 8px}#fda-app .fda-server-summary :is(th,td){padding:8px;text-align:left;border-bottom:1px solid var(--border)}#fda-app .fda-server-summary .latest-card{display:block;padding-block:12px;color:var(--text)}#fda-app .fda-server-summary .latest-card>*{display:block}#fda-app .fda-server-summary .latest-card small{color:var(--text-muted)}#fda-app [data-server-rendered] .table-wrap{overflow-x:auto}#fda-app [data-server-rendered] .latest-card>*{display:block}#fda-app [data-server-rendered] .latest h2{font-size:1.25rem}#fda-app [data-server-rendered] caption{padding-inline:18px}@media print{[data-site-header],.site-footer{display:none!important}#fda-app{padding-top:0}}#fda-app .fda-tour-ring{position:fixed;z-index:990;border:2px solid var(--blue, var(--depth));border-radius:10px;box-shadow:0 0 0 9999px color-mix(in srgb,var(--text) 52%,transparent);pointer-events:none;transition:top .2s ease,left .2s ease,width .2s ease,height .2s ease}#fda-app .fda-tour-card{position:fixed;z-index:991;box-sizing:border-box;padding:18px 18px 14px;border:1px solid var(--line, var(--border));border-radius:12px;background:var(--panel, var(--surface));color:var(--text);box-shadow:0 18px 48px color-mix(in srgb,var(--text) 22%,transparent)}#fda-app .fda-tour-card.is-docked{left:12px;right:12px;bottom:calc(12px + env(safe-area-inset-bottom));top:auto;width:auto}#fda-app .fda-tour-kicker{display:block;font-size:11.5px;font-weight:750;letter-spacing:.08em;color:var(--teal)}#fda-app .fda-tour-card h2{margin:6px 0 4px;font-family:Space Grotesk,system-ui,sans-serif;font-size:18px;font-weight:650;letter-spacing:-.015em;line-height:1.3;color:var(--text)}#fda-app .fda-tour-card p{margin:0;font-size:14px;line-height:1.5;color:var(--text-muted, var(--muted))}#fda-app .fda-tour-actions{display:flex;align-items:center;justify-content:space-between;gap:10px;margin-top:14px;flex-wrap:wrap}#fda-app .fda-tour-actions>span{display:flex;gap:8px;flex-wrap:wrap}#fda-app .fda-tour-skip{padding:0;border:0;background:none;font:inherit;font-size:13.5px;color:var(--text-muted, var(--muted));cursor:pointer}#fda-app .fda-tour-skip:hover{color:var(--blue, var(--depth));text-decoration:underline}#fda-app .fda-tour-btn{box-sizing:border-box;display:inline-flex;align-items:center;min-height:40px;padding:0 14px;border:1px solid var(--line, var(--border));border-radius:8px;background:var(--panel, var(--surface));color:var(--text);font:inherit;font-size:13.5px;font-weight:700;cursor:pointer}#fda-app .fda-tour-btn:hover{border-color:var(--blue, var(--depth));color:var(--blue, var(--depth))}#fda-app .fda-tour-btn.primary{background:var(--text);border-color:var(--text);color:var(--panel, var(--surface))}#fda-app .fda-tour-btn.primary:hover{opacity:.9;color:var(--panel, var(--surface))}@media(prefers-reduced-motion:reduce){#fda-app .fda-tour-ring{transition:none}}#fda-app .fda-tour-start{box-sizing:border-box;display:inline-flex;align-items:center;gap:8px;min-height:40px;padding:0 16px;border:1.5px solid var(--blue, var(--depth));border-radius:8px;background:var(--panel, var(--surface));color:var(--blue, var(--depth));font:inherit;font-size:13.5px;font-weight:700;white-space:nowrap;cursor:pointer}#fda-app .fda-tour-start:hover{background:color-mix(in srgb,var(--blue, var(--depth)) 8%,var(--panel, var(--surface)))}#fda-app .fda-tour-start svg{width:18px;height:18px;flex:none}#fda-app .fda-tour-start[hidden]{display:none}#fda-app .guided-title{position:relative}#fda-app .guided-title>.fda-tour-start{position:absolute;right:0;bottom:0}#fda-app .desk-title>.fda-tour-start{flex:none;margin-bottom:0}@media(max-width:760px){#fda-app .guided-title>.fda-tour-start{position:static;margin-top:10px}#fda-app .desk-title>.fda-tour-start{margin-top:10px}}@media(min-width:900px){#fda-app .commercial:not(.fda-record-commercial)>:is(.wrap,.commercial-in){display:grid;grid-template-columns:minmax(0,1.1fr) minmax(0,1fr);column-gap:clamp(40px,6vw,120px);align-items:end}#fda-app .commercial:not(.fda-record-commercial) :is(.wrap,.commercial-in)>.eyebrow{grid-column:1 / -1}#fda-app .commercial:not(.fda-record-commercial) :is(.wrap,.commercial-in)>h2{grid-column:1;grid-row:2 / span 2;margin-bottom:0;align-self:end}#fda-app .commercial:not(.fda-record-commercial) :is(.wrap,.commercial-in)>p{grid-column:2;grid-row:2;max-width:620px}#fda-app .commercial:not(.fda-record-commercial) :is(.wrap,.commercial-in)>.actions{grid-column:2;grid-row:3}}@media(min-width:900px){#fda-app .commercial.fda-record-commercial{display:grid;grid-template-columns:minmax(0,1.1fr) minmax(0,1fr);column-gap:clamp(40px,6vw,120px);align-items:end}#fda-app .commercial.fda-record-commercial>.eyebrow{grid-column:1 / -1}#fda-app .commercial.fda-record-commercial>h2{grid-column:1;grid-row:2 / span 2;margin-bottom:0;align-self:end}#fda-app .commercial.fda-record-commercial>p{grid-column:2;grid-row:2;max-width:620px}#fda-app .commercial.fda-record-commercial>.actions{grid-column:2;grid-row:3}}#fda-app #fdaShareDialog .fda-share-actions>:is(button,a),#fda-app #fdaShareDialog #fdaShareClose{box-sizing:border-box;display:inline-flex;align-items:center;justify-content:center;gap:8px;min-height:40px;height:40px;padding:0 14px;border:1px solid var(--line, var(--border));border-radius:8px;background:var(--panel, var(--surface));color:var(--text);font-size:13.5px;font-weight:700;line-height:1.2;text-decoration:none}#fda-app #fdaShareDialog .fda-share-actions>:is(button,a):hover,#fda-app #fdaShareDialog #fdaShareClose:hover{border-color:var(--blue, var(--depth));color:var(--blue, var(--depth));background:var(--panel, var(--surface))}#fda-app #fdaShareDialog #fdaShareCopy{background:var(--text);border-color:var(--text);color:var(--panel, var(--surface))}#fda-app #fdaShareDialog #fdaShareCopy:hover{background:var(--text);border-color:var(--text);color:var(--panel, var(--surface));opacity:.9}#fda-app #fdaShareDialog #fdaShareClose{width:40px;min-width:40px;max-width:40px;padding:0;font-size:20px;font-weight:400;flex:none}#fda-app .fda-more{display:none}@media(max-width:1100px){#fda-app.fda-has-more :is(.guided-title,.desk-title){position:relative}#fda-app.fda-has-more :is(.guided-title,.desk-title) h1{padding-right:52px}#fda-app.fda-has-more .fda-more{display:block;position:absolute;right:0;top:30px;z-index:30}#fda-app.fda-has-more :is(.guided-actions,.explorer-search-tools>.fda-share-cta,.explorer-search-tools>.fda-alerts-top,:is(.guided-title,.desk-title)>.fda-tour-start){display:none!important}#fda-app .fda-more-button{box-sizing:border-box;width:40px;height:40px;padding:0;display:inline-flex;align-items:center;justify-content:center;border:1px solid var(--line, var(--border));border-radius:8px;background:var(--panel, var(--surface));color:var(--text);cursor:pointer}#fda-app .fda-more-button svg{width:20px;height:20px}#fda-app .fda-more-button[aria-expanded=true]{border-color:var(--blue, var(--depth));color:var(--blue, var(--depth))}#fda-app .fda-more-menu{position:absolute;right:0;top:46px;min-width:210px;padding:6px;border:1px solid var(--line, var(--border));border-radius:10px;background:var(--panel, var(--surface));box-shadow:0 10px 28px #0d1e3029}#fda-app .fda-more-menu[hidden]{display:none}#fda-app.fda-has-more .fda-more.is-open{z-index:1000}#fda-app .fda-more-menu [role=menuitem]{display:flex;align-items:center;gap:10px;width:100%;min-height:44px;padding:0 12px;border:0;border-radius:6px;background:transparent;color:var(--text);font-size:15px;font-weight:600;text-align:left;cursor:pointer}#fda-app .fda-more-menu [role=menuitem]:is(:hover,:focus-visible){background:var(--soft, var(--surface-2));outline:none}#fda-app .fda-more-menu svg{width:18px;height:18px;flex:none}#fda-app :is(#scopeBar,#guidedScope,#regScope) .scope-label{display:none}#fda-app :is(#scopeBar,#guidedScope,#regScope) :is([data-scope=undo],[data-guided-undo]){display:none}#fda-app .fda-back-row{display:none}}#fda-app :is(a,button,select,summary,[tabindex],input:is([type=checkbox],[type=radio])):focus-visible{outline:2px solid var(--depth);outline-offset:2px}#fda-app{--backdrop: color-mix(in srgb, var(--text) 45%, transparent)}#fda-app dialog::backdrop{background:var(--backdrop)}@media(max-width:1100px){#fda-app.fda-has-more .fda-more.fda-more-inline{position:relative;top:auto;right:auto;flex:none;align-self:center;margin-left:8px;order:2}#fda-app.fda-record-module[data-header=desk] .app-nav .app-nav-inner:has(>.fda-more-inline){flex-wrap:nowrap}#fda-app.fda-record-module[data-header=desk] .app-nav .app-nav-inner:has(>.fda-more-inline)>nav.fda-primary-nav{flex:1 1 auto;width:auto;min-width:0}}#fda-app .fda-carry-dialog .fda-carry-text{margin:0 0 10px;font-size:.95rem;line-height:1.5;color:var(--text-muted, var(--muted))}#fda-app .fda-carry-chips{display:flex;flex-wrap:wrap;gap:6px;margin:0 0 6px;padding:0;list-style:none}#fda-app .fda-carry-chips li{padding:6px 10px;border:1px solid var(--line, var(--border));border-radius:8px;font-size:.85rem;font-weight:600;color:var(--text);background:var(--soft, var(--surface-2))}#fda-app .fda-carry-chips li.more{background:transparent;color:var(--text-muted, var(--muted));font-weight:500}#fda-app .fda-carry-dialog .fda-carry-keep{background:var(--text);border-color:var(--text);color:var(--panel, var(--surface));font-weight:650}#fda-app .fda-carry-dialog .fda-carry-keep:hover{opacity:.9}#fda-app .fda-carry-dialog::backdrop{background:var(--backdrop)}#fda-app .ext-mark{display:inline-block;margin-left:.15em;text-decoration:none}#fda-app .sr-only{position:absolute;width:1px;height:1px;padding:0;margin:-1px;overflow:hidden;clip:rect(0 0 0 0);white-space:nowrap;border:0}#fda-app .fda-db-note{box-sizing:border-box;width:min(100%,var(--fda-wrap, 1440px));margin:0 auto;padding:18px 22px 28px;font-size:.85rem;color:var(--text-muted, var(--muted))}#fda-app .fda-db-note a{color:inherit;text-decoration:underline;text-underline-offset:3px}#fda-app .fda-db-note a:hover{color:var(--text)}#fda-app dialog:is(#alertsDialog,.fda-share-dialog,.fda-evidence-dialog){border-radius:16px}#fda-app :is(#alertsDialog .dialog-head h2,.fda-share-heading h2,.fda-evidence-dialog h2){font-size:24px;line-height:1.2;letter-spacing:-.02em}#fda-app :is(#alertsDialog .dialog-head button,.fda-share-heading button,.fda-evidence-dialog .dialog-close,.fda-evidence-dialog [data-close][aria-label]){box-sizing:border-box;width:40px;height:40px;min-width:40px;min-height:40px;padding:0;display:inline-grid;place-items:center;border-radius:8px;font-size:22px;line-height:1}#fda-app .fda-share-dialog .fda-share-actions :is(button,a){min-height:40px}@media(max-width:400px){#fda-app .fda-share-dialog .fda-share-actions{flex-direction:column}#fda-app .fda-share-dialog .fda-share-actions>*{width:100%}}#fda-app :is(.letter-item,.launch-letter){min-width:0}#fda-app :is(.letter-item strong,.launch-letter-name,.record-context){overflow-wrap:anywhere}