#fda-app[data-header=desk]{--bg:#F5F6F7;--panel:#FFFFFF;--text:#182D40;--muted:#5E7182;--faint:#8998A5;--line:#DCE3E8;--soft:#EDF2F5;--teal:#087660;--teal-wash:#E4F4EE;--blue:#147BB0;font-family:DM Sans,system-ui,-apple-system,Segoe UI,sans-serif;line-height:1.5}#fda-app[data-header=desk] .app-nav{background:var(--bg);border-bottom:0}#fda-app[data-header=desk] .app-nav-inner.fda-nav-frame{flex-wrap:wrap;align-items:center;column-gap:10px;row-gap:14px;min-height:0;padding-top:14px;padding-bottom:14px}#fda-app[data-header=desk] .app-name,#fda-app[data-header=desk] #themeToggle{display:none!important}#fda-app[data-header=desk] .app-nav .fda-primary-nav{order:0;flex:1 1 auto;align-self:stretch;min-height:44px;border-bottom:1px solid var(--line)}#fda-app[data-header=desk] .app-nav .fda-primary-nav a{color:var(--muted);font-weight:600}#fda-app[data-header=desk] .app-nav .fda-primary-nav a:hover{color:var(--text)}#fda-app[data-header=desk] .app-nav .fda-primary-nav a[aria-current=page]{color:var(--text);font-weight:700}#fda-app[data-header=desk] .app-nav .fda-primary-nav a[aria-current=page]:after{height:2px;background:var(--blue);inset:auto 0 -1px}#fda-app[data-header=desk] .guided-actions{order:1;display:flex;gap:10px}#fda-app[data-header=desk] .guided-action{display:inline-flex;align-items:center;justify-content:center;gap:8px;height:40px;padding:0 14px;border:1px solid var(--line);border-radius:8px;background:var(--panel);color:var(--text);font:inherit;font-size:13.5px;font-weight:650;white-space:nowrap;cursor:pointer}#fda-app[data-header=desk] .guided-action:hover{border-color:var(--blue);color:var(--blue)}#fda-app[data-header=desk] .guided-action.primary{background:var(--text);border-color:var(--text);color:var(--panel)}#fda-app[data-header=desk] .guided-action.primary:hover{opacity:.9;color:var(--panel)}#fda-app[data-header=desk] .guided-action .control-icon{width:16px;height:16px}#fda-app[data-header=desk] .app-nav .search{order:2;flex:1 1 100%;width:auto;max-width:none;min-width:0;margin:0;height:52px;padding:0 10px 0 15px;border:1px solid var(--line);border-radius:9px;background:var(--panel)}#fda-app[data-header=desk] .app-nav .search input{font-size:15px}#fda-app[data-header=desk] .app-nav .search:focus-within{border-color:var(--blue);box-shadow:0 0 0 3px color-mix(in srgb,var(--blue) 15%,transparent)}#fda-app[data-header=desk] .app-nav .search-suggestions{left:0;right:auto;width:min(560px,100%)}@media(max-width:760px){#fda-app[data-header=desk] .app-nav .fda-primary-nav{flex:1 1 100%;overflow-x:auto;scrollbar-width:none}#fda-app[data-header=desk] .guided-actions{flex:1 1 100%}#fda-app[data-header=desk] .guided-action{flex:1 1 0;padding:0 10px;font-size:13px}#fda-app[data-header=desk] .app-nav .search{height:46px}}#fda-app[data-header=desk] .app-nav-inner.fda-nav-frame{width:min(1232px,calc(100% - 80px));max-width:none;margin-inline:auto;padding-inline:0}@media(max-width:1150px){#fda-app[data-header=desk] .app-nav-inner.fda-nav-frame{width:calc(100% - 48px)}}@media(max-width:740px){#fda-app[data-header=desk] .app-nav-inner.fda-nav-frame{width:calc(100% - 36px)}}#fda-app[data-header=desk] .guided-title{width:min(1232px,calc(100% - 80px));margin:28px auto 6px}#fda-app[data-header=desk] .guided-title-eyebrow{display:block;font-size:12px;font-weight:750;letter-spacing:.1em;color:var(--teal);line-height:1.4}#fda-app[data-header=desk] .guided-title-name{font-family:Space Grotesk,system-ui,-apple-system,Segoe UI,sans-serif;font-size:35px;font-weight:600;letter-spacing:-.025em;line-height:1.2;margin:6px 0 4px;color:var(--text)}#fda-app[data-header=desk] .guided-title-lede{font-size:16px;color:var(--muted);margin:0}#fda-app[data-header=desk] .guided-title-fresh{font-size:13px;color:var(--muted);opacity:.85;margin:6px 0 0}@media(max-width:1150px){#fda-app[data-header=desk] .guided-title{width:calc(100% - 48px)}}@media(max-width:740px){#fda-app[data-header=desk] .guided-title{width:calc(100% - 36px);margin-top:20px}#fda-app[data-header=desk] .guided-title-name{font-size:28px}#fda-app[data-header=desk] .guided-title-lede{font-size:15px}}#fda-app[data-header=desk] .guided-title-name{margin:6px 0 4px}#fda-app[data-header=desk] h1.guided-title-name{font-size:35px;max-width:none}#fda-app[data-header=desk] .letters-view{padding-top:8px}#fda-app[data-header=desk] .letters-view .table-toolbar{display:flex;align-items:center;flex-wrap:wrap;gap:12px 16px;margin-bottom:16px}#fda-app[data-header=desk] .letters-view .table-toolbar>.small{margin-left:auto}#fda-app[data-header=desk] .letters-chips{display:flex;flex-wrap:wrap;gap:6px}#fda-app[data-header=desk] .letter-grid{display:grid;grid-template-columns:repeat(auto-fill,minmax(270px,1fr));gap:14px}#fda-app[data-header=desk] .letter-item{display:flex;flex-direction:column;gap:6px;padding:18px 18px 15px;border:1px solid var(--line);border-radius:10px;background:var(--panel);color:var(--text);text-decoration:none;transition:border-color .15s,background .15s}#fda-app[data-header=desk] .letter-item:hover{border-color:var(--blue);background:color-mix(in srgb,var(--blue) 6%,var(--panel));text-decoration:none}#fda-app[data-header=desk] .letter-item-top{display:flex;align-items:center;justify-content:space-between;gap:10px;margin-bottom:2px}#fda-app[data-header=desk] .letter-item .family{display:inline-block;padding:3px 7px;border-radius:4px;font-size:12px;font-weight:700;letter-spacing:.02em;background:color-mix(in srgb,var(--teal) 12%,var(--panel));color:var(--teal)}#fda-app[data-header=desk] .letter-item .family-device{background:color-mix(in srgb,var(--blue) 12%,var(--panel));color:var(--blue)}#fda-app[data-header=desk] .letter-item .family-bio{background:color-mix(in srgb,var(--gold) 14%,var(--panel));color:var(--gold)}#fda-app[data-header=desk] .letter-item-view{display:inline-flex;align-items:center;gap:5px;font-size:14px;font-weight:600;color:var(--blue)}#fda-app[data-header=desk] .letter-item-view svg{width:14px;height:14px}#fda-app[data-header=desk] .letter-item strong{font-family:Space Grotesk,sans-serif;font-size:16px;font-weight:700;letter-spacing:-.015em;line-height:1.3}#fda-app[data-header=desk] .letter-item .record-context{font-size:14px;line-height:1.45;color:var(--muted)}#fda-app[data-header=desk] .letter-item-dates{display:flex;gap:22px;margin-top:auto;padding-top:8px;font-size:14px}#fda-app[data-header=desk] .letter-item-dates small{display:block;font-size:11px;font-weight:700;letter-spacing:.06em;text-transform:uppercase;color:var(--muted)}@media(max-width:740px){#fda-app[data-header=desk] h1.guided-title-name{font-size:28px}#fda-app[data-header=desk] .letters-view .table-toolbar>.small{margin-left:0;flex-basis:100%}}#fda-app[data-header=desk] .app-nav .search{gap:10px}#fda-app[data-header=desk] .app-nav .search .search-icon{width:16px;height:16px;flex:none;color:var(--teal)}#fda-app[data-header=desk] .app-nav .search input::placeholder{color:var(--faint)}#fda-app[data-header=desk] .app-nav .search-suggestions{left:0;right:0;width:auto;max-width:none;max-height:min(460px,65vh);overflow:auto}#fda-app[data-header=desk] .search-suggestions a[data-suggestion-letter]{display:block;width:100%;text-align:left;padding:10px;border-radius:7px;color:var(--text);font-size:.88rem;text-decoration:none}#fda-app[data-header=desk] .search-suggestions a[data-suggestion-letter]:hover{background:var(--soft)}#fda-app[data-header=desk] .search-suggestions .kicker{margin-top:4px}#fda-app[data-header=desk] .search-suggestions{padding:6px}#fda-app[data-header=desk] .search-suggestions .sg-head{font-size:11px;font-weight:700;letter-spacing:.12em;text-transform:uppercase;color:var(--muted);padding:6px 8px 4px}#fda-app[data-header=desk] .search-suggestions .sg-item{display:grid;grid-template-columns:118px minmax(0,1fr) auto;gap:10px;align-items:baseline;width:100%;text-align:left;background:none;border:0;border-radius:6px;padding:8px;font-size:13.5px;color:var(--text);cursor:pointer}#fda-app[data-header=desk] .search-suggestions .sg-item:hover,#fda-app[data-header=desk] .search-suggestions .sg-item.act{background:color-mix(in srgb,var(--teal) 9%,transparent)}#fda-app[data-header=desk] .search-suggestions .sg-item.act{box-shadow:inset 3px 0 0 var(--teal)}#fda-app[data-header=desk] .search-suggestions .sg-g{font-size:11.5px;color:var(--teal);font-weight:600;white-space:nowrap;overflow:hidden;text-overflow:ellipsis}#fda-app[data-header=desk] .search-suggestions .sg-l{min-width:0;overflow:hidden;text-overflow:ellipsis;white-space:nowrap;font-weight:500}#fda-app[data-header=desk] .search-suggestions .sg-s{color:var(--muted);font-weight:400}#fda-app[data-header=desk] .search-suggestions .sg-n{font-size:12.5px;color:var(--muted);white-space:nowrap}#fda-app[data-header=desk] .search-suggestions .sg-item.on .sg-l{color:var(--teal)}#fda-app[data-header=desk] .search-suggestions .sg-foot{font-size:12px;color:var(--muted);padding:8px 8px 4px;border-top:1px solid var(--line);margin-top:4px}@media(max-width:740px){#fda-app[data-header=desk] .search-suggestions .sg-item{grid-template-columns:76px minmax(0,1fr) auto;gap:7px}#fda-app[data-header=desk] .search-suggestions .sg-l{white-space:normal}}#fda-app[data-header=desk] .scope-bar{order:3;flex:1 1 100%;display:flex;gap:10px 12px;align-items:center;flex-wrap:wrap;min-height:52px;padding:10px 0 0;border-top:1px solid var(--line)}#fda-app[data-header=desk] .scope-label{font-size:12px;letter-spacing:.07em;font-weight:750;color:var(--muted);white-space:nowrap}#fda-app[data-header=desk] .scope-chips{display:flex;gap:6px;flex:1;flex-wrap:wrap;align-items:center;min-width:0}#fda-app[data-header=desk] .scope-chip{display:inline-flex;align-items:center;gap:7px;padding:5px 8px;border:1px solid color-mix(in srgb,var(--teal) 22%,transparent);border-radius:5px;background:color-mix(in srgb,var(--teal) 10%,var(--panel));color:var(--teal);font:inherit;font-size:13px;font-weight:600;cursor:pointer}#fda-app[data-header=desk] .scope-chip:hover{border-color:var(--teal)}#fda-app[data-header=desk] .scope-chip .icon{width:12px;height:12px}#fda-app[data-header=desk] .all-records{font-size:14px;color:var(--muted)}#fda-app[data-header=desk] .scope-actions{display:flex;align-items:center;gap:14px;margin-left:auto;font-size:13px}#fda-app[data-header=desk] .scope-action{border:0;background:none;padding:0;color:var(--blue);font:inherit;font-size:13px;font-weight:650;cursor:pointer}#fda-app[data-header=desk] .scope-action:hover{text-decoration:underline}#fda-app[data-header=desk] .result-count{padding-left:13px;border-left:1px solid var(--line);white-space:nowrap;color:var(--text)}@media(max-width:760px){#fda-app[data-header=desk] .scope-bar.is-empty{display:none}#fda-app[data-header=desk] .scope-label{width:100%}#fda-app[data-header=desk] .scope-actions{width:100%;margin:0}#fda-app[data-header=desk] .result-count{margin-left:auto;border:0;padding:0}}#fda-app[data-header=desk] #toast{top:50%;bottom:auto;left:50%;transform:translate(-50%,-50%);border-radius:12px;font-size:15px;font-weight:600;padding:15px 24px}#fda-app[data-header=desk] #recordTheme{display:none!important}#fda-app[data-header=desk] .wrap,#fda-app[data-header=desk] .guided-title,#fda-app[data-header=desk] .app-nav-inner.fda-nav-frame{width:min(1756px,calc(100% - 44px))}#fda-app[data-header=desk] .guided-title{margin-bottom:17px}#fda-app[data-header=desk] .app-nav .search{margin-top:7px}#fda-app[data-header=desk] .scope-bar{margin-top:2px}@media(max-width:1150px){#fda-app[data-header=desk] .wrap,#fda-app[data-header=desk] .guided-title,#fda-app[data-header=desk] .app-nav-inner.fda-nav-frame{width:calc(100% - 44px)}}@media(max-width:760px){#fda-app[data-header=desk] .wrap,#fda-app[data-header=desk] .guided-title,#fda-app[data-header=desk] .app-nav-inner.fda-nav-frame{width:calc(100% - 28px)}}#fda-app[data-header=desk] .app-nav .fda-primary-nav a[aria-current=page]{font-weight:600}#fda-app[data-header=desk] .guided-action{box-sizing:border-box;height:40px;min-height:40px;font-weight:700;line-height:1.5}#fda-app[data-header=desk] .guided-title-fresh{color:var(--faint);opacity:1}#fda-app[data-header=desk] .scope-chip{background:var(--teal-wash);border-color:#08766038}#fda-app[data-header=desk] .guided-action[data-fda-share]{gap:10px}#fda-app[data-header=desk] .guided-action[data-fda-share] .control-icon{width:18px;height:18px;flex:0 0 18px}#fda-app[data-header=desk] .guided-action.primary .control-icon{width:16px;height:16px;flex:0 0 18px}#fda-app[data-header=desk] :is(#guidedScope,#regScope) .result-count b{font-weight:700}@media(max-width:760px){#fda-app[data-header=desk] .guided-title{margin-bottom:13px}#fda-app[data-header=desk] .guided-title~.app-nav .app-nav-inner{padding-top:6px}}#fda-app[data-header=desk] .launch{padding:8px 0 56px}#fda-app[data-header=desk] .launch .sr-only{position:absolute;width:1px;height:1px;overflow:hidden;clip:rect(0 0 0 0);white-space:nowrap}#fda-app[data-header=desk] .launch .control-icon{width:16px;height:16px;flex:0 0 16px}#fda-app[data-header=desk] .launch-path{list-style:none;margin:18px 0 0;padding:0;display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:14px}#fda-app[data-header=desk] .launch-door{display:flex;flex-direction:column;gap:8px;padding:22px 22px 20px;border:1px solid var(--line);border-radius:10px;background:var(--panel)}#fda-app[data-header=desk] .launch-door>.control-icon{width:24px;height:24px;flex-basis:24px;margin:6px 0 2px;color:var(--blue)}#fda-app[data-header=desk] .launch-door.is-primary{border-color:var(--text);box-shadow:0 0 0 1px var(--text)}#fda-app[data-header=desk] .launch-door.is-primary>.control-icon{color:var(--teal)}#fda-app[data-header=desk] .launch-step{font-size:12px;font-weight:750;letter-spacing:.08em;text-transform:uppercase;color:var(--muted)}#fda-app[data-header=desk] .launch-door h3{margin:0;font-family:Space Grotesk,system-ui,-apple-system,Segoe UI,sans-serif;font-size:22px;font-weight:600;letter-spacing:-.02em;line-height:1.25;color:var(--text)}#fda-app[data-header=desk] .launch-door p{margin:0 0 6px;font-size:15px;line-height:1.5;color:var(--muted)}#fda-app[data-header=desk] .launch-link{display:inline-flex;align-items:center;gap:6px;margin-top:auto;font-size:14.5px;font-weight:700;color:var(--blue);text-decoration:none}#fda-app[data-header=desk] .launch-link:hover{text-decoration:underline}#fda-app[data-header=desk] .launch-button{box-sizing:border-box;display:inline-flex;align-items:center;justify-content:center;gap:8px;align-self:flex-start;height:40px;margin-top:auto;padding:0 16px;border-radius:8px;background:var(--text);color:var(--panel);font-size:14px;font-weight:700;line-height:1.5;text-decoration:none}#fda-app[data-header=desk] .launch-button:hover{opacity:.9;color:var(--panel);text-decoration:none}#fda-app[data-header=desk] .launch-head{margin:56px 0 18px;max-width:720px}#fda-app[data-header=desk] .launch-head .eyebrow{display:block;font-size:12px;font-weight:750;letter-spacing:.1em;text-transform:uppercase;color:var(--teal)}#fda-app[data-header=desk] .launch-head h2{margin:6px 0;font-family:Space Grotesk,system-ui,-apple-system,Segoe UI,sans-serif;font-size:26px;font-weight:600;letter-spacing:-.02em;line-height:1.25;color:var(--text)}#fda-app[data-header=desk] .launch-head p{margin:0;font-size:15px;line-height:1.5;color:var(--muted)}#fda-app[data-header=desk] .launch-letters{list-style:none;margin:0 0 16px;padding:0;display:grid;grid-template-columns:repeat(3,minmax(0,1fr));gap:14px}#fda-app[data-header=desk] .launch-letter{display:flex;flex-direction:column;gap:6px;padding:18px 18px 16px;border:1px solid var(--line);border-radius:10px;background:var(--panel)}#fda-app[data-header=desk] .launch-letter .letter-item-top small{font-size:13px;color:var(--muted)}#fda-app[data-header=desk] .launch-letter .family{display:inline-block;padding:3px 7px;border-radius:4px;font-size:12px;font-weight:700;letter-spacing:.02em;background:var(--teal-wash);color:var(--teal)}#fda-app[data-header=desk] .launch-letter .family-device{background:color-mix(in srgb,var(--blue) 12%,var(--panel));color:var(--blue)}#fda-app[data-header=desk] .launch-letter .family-bio{background:color-mix(in srgb,var(--gold) 14%,var(--panel));color:var(--gold)}#fda-app[data-header=desk] .launch-letter-name{font-family:Space Grotesk,system-ui,-apple-system,Segoe UI,sans-serif;font-size:17px;font-weight:700;letter-spacing:-.015em;line-height:1.3;color:var(--text);text-decoration:none}#fda-app[data-header=desk] .launch-letter-name:hover{color:var(--blue)}#fda-app[data-header=desk] .launch-letter-meta{font-size:14px;color:var(--muted)}#fda-app[data-header=desk] .launch-like{display:flex;align-items:center;justify-content:space-between;gap:10px;margin-top:auto;padding-top:12px;border-top:1px solid var(--soft);font-size:14px;font-weight:650;line-height:1.4;color:var(--text);text-decoration:none}#fda-app[data-header=desk] .launch-like:hover{color:var(--blue)}#fda-app[data-header=desk] .launch-empty{margin:0 0 16px;padding:18px;border:1px dashed var(--line);border-radius:10px;color:var(--muted)}#fda-app[data-header=desk] .launch-statement{padding:88px 0 40px}#fda-app[data-header=desk] .launch-statement p{margin:0;max-width:22ch;font-family:Space Grotesk,system-ui,-apple-system,Segoe UI,sans-serif;font-size:clamp(32px,4.4vw,56px);font-weight:600;letter-spacing:-.03em;line-height:1.12;color:var(--text)}#fda-app[data-header=desk] .launch-questions{list-style:none;margin:0;padding:0;display:grid;grid-template-columns:repeat(3,minmax(0,1fr));column-gap:28px;border-top:1px solid var(--line)}#fda-app[data-header=desk] .launch-questions li{border-bottom:1px solid var(--line)}#fda-app[data-header=desk] .launch-questions a{display:grid;grid-template-columns:1fr auto;gap:4px 14px;height:100%;box-sizing:border-box;padding:18px 18px 18px 0;color:var(--text);text-decoration:none}#fda-app[data-header=desk] .launch-questions b{font-family:Space Grotesk,system-ui,-apple-system,Segoe UI,sans-serif;font-size:16px;font-weight:600}#fda-app[data-header=desk] .launch-questions span{grid-column:1;font-size:14px;line-height:1.45;color:var(--muted)}#fda-app[data-header=desk] .launch-questions .control-icon{grid-column:2;grid-row:1 / span 2;align-self:center;color:var(--blue)}#fda-app[data-header=desk] .launch-questions a:hover b{color:var(--blue)}@media(max-width:900px){#fda-app[data-header=desk] .launch-path{grid-template-columns:1fr}#fda-app[data-header=desk] .launch-letters,#fda-app[data-header=desk] .launch-questions{grid-template-columns:1fr 1fr}}@media(max-width:560px){#fda-app[data-header=desk] .launch-questions,#fda-app[data-header=desk] .launch-letters{grid-template-columns:1fr}#fda-app[data-header=desk] .launch-head{margin-top:44px}#fda-app[data-header=desk] .launch-statement{padding:64px 0 24px}}#fda-app[data-header=desk][data-view=method] :is(#searchForm,#guidedScope){display:none}#fda-app[data-header=desk] .method-view{padding:22px 0 56px}#fda-app[data-header=desk] .method-view .method-head{max-width:none;margin:0 0 16px;padding:0;text-align:left}#fda-app[data-header=desk] .method-head h2{margin:0;font-family:Space Grotesk,system-ui,-apple-system,Segoe UI,sans-serif;font-size:24px;font-weight:600;letter-spacing:-.015em;line-height:1.1;color:var(--text)}#fda-app[data-header=desk] .method-head p{margin:4px 0 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